The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D
Main questions it aims to answer are:
1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will
a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done.
Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV
Male patients with of Parkinson's disease diagnosed by neurologist with unilateral or bilateral involvement and mild to moderate disability according to Hoehn and Yahr (H-Y) scale (I-III)
Age: 51-70 years
BMI: 18.5-24.9 kg/m2
Vitamin D3 deficient or insufficient
Patients with a history of drug abuse including alcoholism.
Patients on following drugs will be excluded-
Antioxidant vitamin supplements
Lipid lowering medications