Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorNantes University Hospital

About this trial

Benzodiazepines or related drug (BZDR) are consumed for hypnotic or anxiolytic purposes in most cases. The consequences of BZDR are multiple with an increased risk of daytime sedation, balance disorders leading to falls and fractures, cognitive disorders, road accidents and dementia. Given their comorbidities, physiological changes, and multiple medications, the elderly are more at risk of suffering from BZDR adverse events.

Interprofessional collaboration has shown efficacy in improving prescribing appropriateness and may affect patients outcomes positively. Morever, motivational interviews (MI) may reduce the extent of substance abuse compared to no intervention.

Eligibility criteria

Qualifiers

outpatients aged 65 and over

followed by the general practitioner and the pharmacist of the GP-PO pair

having a prescription for an anxiolytic or hypnotic BZDR prescribed at least 4 times in the past year

the last prescription being less than 3 months old

Disqualifiers

patients living in an institution

participating in a clinical trial

with epilepsy

active depression

Trial design

Treatments tested in this trial

  • GP - pharmacist collaboration and pharmacist motivational interviewing

Treatment groups

400 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Nantes University Hospital

Lead sponsor

Université de Nantes

Collaborator