This clinical study evaluates whether a supervised, multimodal therapeutic exercise program started before chemotherapy and continued during treatment can improve treatment outcomes in patients aged 35 to 65 years with breast, lung, or colon cancer.
The study hypothesis is that participation in this exercise program improves tolerance to chemotherapy, allowing patients to receive more than 85% of the planned relative dose intensity. In addition, the program is expected to enhance treatment effectiveness by increasing the rate of complete radiological response.
The main objective of the study is to assess the effectiveness of a supervised, multimodal therapeutic exercise program performed before and during chemotherapy in improving both treatment tolerance and treatment efficacy in patients with breast, lung, and colon cancer.
Women and men aged 35 to 65 years
Diagnosed with stage II, III, or IV breast, lung, or colon cancer
Scheduled to start neoadjuvant chemotherapy
Able and willing to provide written informed consent
Musculoskeletal or neurological disorders that prevent proper execution of the exercises
Uncontrolled infections or symptoms
Comorbidities such as chronic obstructive pulmonary disease (COPD), respiratory failure, or recent cardiovascular events within the past 6 months
Body mass index (BMI) over 35
University of Vic - Central University of Catalonia
Lead sponsor
Col·legi Fisioterapeutes de Catalunya
Collaborator