About this trial
Intercostal nerve cryoanalgesia has become a popular method for managing postoperative pain after Nuss procedure, showing greater effectiveness compared to epidural anesthesia and patient-controlled analgesia. However, the optimal duration of cryoanalgesia remains unknown. Most protocols use a two-minute cryoablation, although histological studies show similar changes with both one-minute and two-minute applications.
This is a pilot, single-center, randomized, double-blind study comparing the effectiveness of one-minute versus two-minute cryoanalgesia in treating pain in patients undergoing correction of pectus excavatum using the Nuss procedure. The aim of the project is to evaluate the validity of the research procedure and determine the sample size for the main study. Preliminary data on postoperative pain intensity, opioid consumption, duration of surgery, length of hospital stay, and complications will be analyzed.
Eligibility criteria
Qualifiers
Pectus excavatum repair with MIRPE
Written consent for corrective surgery with intraoperative cryoanalgesia
Written consent to participate in the study
Age >12 and < 18 years
Disqualifiers
History of previous thoracic surgeries
Reoperation for chest deformity
Contraindication for cryoanalgesia
Presence of other conditions that may affect the course of the procedures and the assessment of their effectiveness and safety
Trial design
Treatments tested in this trial
- One minute intercostal nerves cryoanalgesia
- Two minutes intercostal nerves cryoanalgesia