Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-13
SponsorBahçeşehir University

About this trial

The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin asetat (DDAVP) treatment prescribed by a pediatric urologist. The study aims to investigate whether SPFMR can reduce the frequency and severity of enuresis episodes and whether it can also reduce relapse rates in the short- and long-term follow-up. The main questions the study seeks to answer are:

* Does SPFMR reduce the frequency and severity of enuresis episodes in children with PMNE? * Does SPFMR treatment reduce relapse rates in children with PMNE in the long term? Researchers will compare the group receiving SPFMR in addition to DDAVP treatment with a control group receiving only DDAVP treatment. This comparison will help evaluate the effect of SPFMR on the severity of enuresis episodes and relapse rates.

Participants will:

* Receive DDAVP treatment (SPFMR group and Control group) * Participate in SPFMR sessions ( SPFMR group) * Keep a diary of enuresis frequency and severity * Assess relapse during short- and long-term follow-up

The hypotheses of the study are:

H0: Adding SPFMR to desmopressin treatment for children with PMNE has no short-term effect on the severity of enuresis episodes.

H1: Adding SPFMR to desmopressin treatment for children with PMNE has a short-term effect on the severity of enuresis episodes.

H0: Adding SPFMR to desmopressin treatment for children with PMNE has no long-term effect on the severity of enuresis episodes.

H2: Adding SPFMR to desmopressin treatment for children with PMNE has a long-term effect on the severity of enuresis episodes.

Eligibility criteria

Qualifiers

Being between 7 and 13 years old

Diagnosed with primary MNE by a pediatric urology department within the last 6 months

No urinary tract infection verified by laboratory tests

Ability to communicate in Turkish and absence of mental deficit

Disqualifiers

Presence of orthopedic conditions preventing evaluation

Anatomical anomalies in the urinary system

History of urinary system surgery

Neurological disorders

Trial design

Treatments tested in this trial

  • Structured pelvic floor rehabilitation

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Bahçeşehir University

Lead sponsor

Private Selcuk Sılay Pediatric Urology Clinic

Collaborator

Medipol Acıbadem Regional Hospital

Collaborator