Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.

ConditionSpine Infection

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorNational Cheng-Kung University Hospital

About this trial

This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation.

Eligibility criteria

Qualifiers

Patients who were diagnosed with lumbar spinal stenosis need to undergo posterior lumbar decompression with fusion surgery.

Disqualifiers

People who are allergic to disinfectants (Providine or CHG)

The surgical site has been operated before.

Patients under active infection status.

Trial design

Treatments tested in this trial

Povidone-iodine solution; chlorhexidine gluconate

Treatment groups

105 Participants

are divided into 3 treatment groups

Sponsors and collaborators

National Cheng-Kung University Hospital

Lead sponsor

Source ClinicalTrials.gov