Effectiveness of Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes: A Non-Inferiority RCT

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorThe Hong Kong Polytechnic University

About this trial

The goal of this clinical trial is to determine the effectiveness of Tai Chi training and acupuncture on the migraine attacks and structural brain changes in women with episodic migraine.

Researchers will compare Tai Chi training to acupuncture treatment in a randomized controlled trial with 132 female participants. Participants will:

* Be randomly assigned to either the Tai Chi group or the acupuncture group. * Undergo a 24-week intervention, with structured sessions for Tai Chi or scheduled acupuncture treatments. * Complete assessments through migraine diaries, questionnaires, physical measurements, MRI and TCD scans at various time points.

The study ensures participant safety through close monitoring, with medical support available in case of discomfort. Data confidentiality will be maintained, with encrypted storage and restricted access for research purposes.

Eligibility criteria

Qualifiers

Chinese women aged 18 years and above;

Diagnosed with episodic migraines, with or without aura, according to the International Classification of Headache Disorders, 3rd edition (ICHD-3);

Migraine attack frequency ranging from 2 to 14 days per month (≥15 days/month is classified as chronic migraine and is not included in this study);

Assessed by a sports specialist as capable of engaging in moderate physical activity;

Disqualifiers

Unable to engage in moderate physical activity;

Comorbid with other neurological disorders;

Experiencing non-migraine headaches for more than 5 days per month;

Previous practice of Tai Chi or other mind-body exercises (such as yoga, biofeedback, meditation, etc.);

Trial design

Treatments tested in this trial

  • Tai Chi training
  • Acupuncture

Treatment groups

132 Participants
are divided into 2 treatment groups