Effects of 60-day-6° Head-down Bed Rest on Cartilage and Function of the Knee Joint
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age25-50
SponsorPeking University Third Hospital
About this trial
Objective: To investigate the effects of long-term simulated unloading in bed on articular cartilage quality based on functional magnetic resonance imaging (FMRI) and Knee joint function.
Eligibility criteria
Qualifiers
(1) male; (2) age 25-50 years old; (3) height between 160-175 cm, weight ≥50kg, and BMI between 18.5-26 kg/m²; (4) good general health status.
Disqualifiers
(1) history of alcoholism; (2) smoking ≥5 cigarettes/day in the 3 months before the test; (3) drug dependence or use of medications affecting bone metabolism within 2 weeks before screening; (4) presence of metal implants, severe vertigo, or severe snoring.
Trial design
Treatments tested in this trial
- 60-day-6° head-down bed rest
Treatment groups
26 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov