Effects of a Classic High-frequency rTMS Treatment Versus a Deep rTMS Treatment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Henri Laborit
About this trial
The main objective is to demonstrate that dTMS is more efficient than high frequency rTMS with a conventional coil.
The patient will receive treatment arm A or B :
Arm A : classic rTMS treatment (use of the 8-shaped coil) and standard therapy Arm B: treatment with deep rTMS (use of the H-shaped coil (helmet)) and standard therapies.
20 rTMS sessions are planned (5 sessions per week) and 3 follow-up visits : at Day 30, Day 60 and Day 90.
Eligibility criteria
Qualifiers
Volunteer subjects over 18 years old
Having signed a free and informed consent
Having a diagnostic of caracterised depressive episod recurrent or isolated according to DSM IV criteria (A.P.A 1994).
Having an antidepressant treatment not modified since 3 weeks
Disqualifiers
Depression with psychotic caracteristics
Co-morbid diagnosis according to axis I (DSM IV) of schizophrenia, dependence (or abuse) on alcohol and / or another substance (lifetime)
Patient who has already undergone seismotherapy for current episode and non-responder to this treatment
Patient hospitalized under duress or under legal protection (guardianship, curatorship)
Trial design
Treatments tested in this trial
- classic rTMS using the 8-shaped coil
- deep rTMS using the H1-shaped coil
Treatment groups
152 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov