Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Sao Paulo

About this trial

The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.

Eligibility criteria

Qualifiers

Obesity (grade II and III classified according to Body Mass Index)

Periodontitis stage II to IV

Presence of at least 20 teeth excluding 3rd molars.

Disqualifiers

Smokers

Alcohol or drugs consumption

Kidney disorders

Pregnancy or lactation

Trial design

Treatments tested in this trial

  • antimicrobial photodynamic therapy (aPDT)
  • Control

Treatment groups

24 Participants
are divided into 2 treatment groups

Sponsors and collaborators