Effects of Beverage Volume, Glycerol Concentration, and Sodium Concentration on Fluid Balance in Healthy Euhydrated Men and Women at Rest

ConditionFluid Balance
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorPepsiCo Global R&D

About this trial

The presence of certain ingredients such as sodium and glycerol can facilitate retention of the fluid consumed via renal water reabsorption. To maintain overall whole-body fluid balance, it is important that ingested fluid is retained in the body instead of losing it through urination.

The purpose of this study is to determine the effect of sodium and glycerol concentrations at various fluid intake volumes on fluid balance in healthy, euhydrated men and women.

Eligibility criteria

Qualifiers

Subject is male or female

If female, subject is not pregnant

Subject is 18-50 years of age, inclusive

Subject is at least recreationally active (engaged in light to moderate-intensity, intermittent, or steady-state exercise at least 3 days per week for at least 30 min at a time)

Disqualifiers

Subject has participated in a clinical trial within the past 30 days

Subject has participated in any PepsiCo trial within past 6 months

Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk

Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any Gatorade product. If subject is unsure if a company would be considered a competitor to Gatorade, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.

Trial design

Treatments tested in this trial

  • Placebo beverage, kiwi-strawberry flavor
  • Electrolyte solution without glycerol beverage 1
  • Electrolyte solution without glycerol beverage 2
  • Electrolyte solution without glycerol beverage 3
  • Electrolyte solution with glycerol beverage 1
  • Electrolyte solution with glycerol beverage 2
  • Electrolyte solution with glycerol beverage 3
  • Base with glycerol, no electrolytes beverage 1
  • Base with glycerol, no electrolytes beverage 2
  • Base with glycerol, no electrolytes beverage 3

Treatment groups

80 Participants
are divided into 10 treatment groups

10

Treatment groups

See each treatment group below.

Sponsors and collaborators