Effects of Diaphragmatic and Abdominal Neuromuscular Electrical Stimulation in Post-PCI Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-75
SponsorRiphah International University

About this trial

This study is a randomized controlled trial designed to evaluate the effects of combined diaphragmatic and abdominal neuromuscular electrical stimulation (NMES) on arterial blood gases, pulmonary function, left ventricular ejection fraction, and functional capacity in patients following percutaneous coronary intervention (PCI). A total of 42 participants will be randomly allocated into two groups: an intervention group receiving NMES along with standard cardiac rehabilitation, and a control group receiving standard rehabilitation alone. The intervention will be administered for 30 minutes per session, five days per week, over a period of two weeks. Outcome measures will include arterial blood gas parameters (PaO₂, PaCO₂, SaO₂), spirometry indices (FVC, FEV₁, PEFR), ejection fraction assessed by echocardiography, and functional capacity measured using the 6-minute walk test. Assessments will be conducted at baseline and post-intervention. The study aims to determine whether NMES can serve as an effective adjunct to conventional cardiac rehabilitation in improving respiratory and functional outcomes in post-PCI patients.

Eligibility criteria

Qualifiers

Patients aged 40-75 years

Patients who have undergone successful percutaneous coronary intervention (PCI) for stable or acute coronary syndrome

Hemodynamically stable (no inotropic support, no active arrhythmias)

Left ventricular ejection fraction (LVEF) ≥ 35%

Disqualifiers

Significant arrhythmias or pacemaker/implantable defibrillator not cleared for NMES

Severe pulmonary disease (e.g., advanced COPD, pulmonary fibrosis) affecting lung function independently

Neuromuscular disorders interfering with NMES application

Recent stroke or severe cognitive impairment limiting participation

Trial design

Treatments tested in this trial

  • Neuromuscular Electrical Stimulation (NMES)
  • Standard Cardiac Rehabilitation

Treatment groups

42 Participants
are divided into 2 treatment groups

Locations

This trial has no locations