This randomized controlled study in patients with post-stroke dysphagia aims to determine the optimal stimulation frequency of electroacupuncture of the suprahyoid muscles and to elucidate the underlying neural mechanisms. Participants will be assigned to low-frequency (2 Hz), medium-frequency (50 Hz), or high-frequency (100 Hz) electroacupuncture groups. Therapeutic efficacy will be assessed using the Kubota water-drinking test, videofluoroscopic swallowing study (VFSS), and ultrasonography to identify the optimal frequency. In parallel, diffusion tensor imaging (DTI) will be used to evaluate changes in fiber connectivity between swallowing-related cortical regions (bilateral precentral gyrus, insula, supramarginal gyrus, and frontal lobe) and the medullary nucleus tractus solitarius, thereby exploring neural network remodeling and providing mechanistic evidence to inform clinical practice.
Diagnosis: Patients diagnosed with cerebral infarction confirmed by CT or MRI.
Dysphagia Screening: Presence of varying degrees of dysphagia as screened by the Water Swallow Test (WST).
Clinical Status: Conscious and stable vital signs, with the ability to cooperate with the treatment.
Age: Aged between 18 and 80 years.
Dysphagia Etiology: Patients with dysphagia caused by etiologies other than cerebral infarction.
MRI Contraindications: Patients with metal implants or pacemakers in the body (contraindications for MRI).
Bleeding Risk: Patients with bleeding tendencies or coagulation disorders.
Blood Pressure: Patients with uncontrolled hypertension (systolic blood pressure > 180 mmHg or diastolic blood pressure > 120 mmHg).
Kaili Chen
Lead sponsor
The Third Affiliated hospital of Zhejiang Chinese Medical University
Sponsor institution