Effects of E-cigarette Use on Health
ConditionElectronic Cigarette Use
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21+
SponsorUniversity of Wisconsin, Madison
About this trial
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will quantify the effects of long-term ENDS use on validated and novel biomarkers of cardiovascular and pulmonary disease and how they are influenced by use heaviness, age, body weight, and co-use of other products. This study will produce the most informative evidence to date on how long-term ENDS use affects cardiovascular and pulmonary health.
Eligibility criteria
Qualifiers
greater than or equal to 21 years of age
has vaped a nicotine e-cigarette product at least 2 days/week for most weeks for greater than or equal to 12 months
plans to remain in catchment area for greater than or equal to 3 years
smoked 5 or fewer tobacco cigarettes in the past 6 months
Disqualifiers
serious CV, pulmonary, or other medical problems (e.g., moderate or severe aortic stenosis, class III or IV heart failure, blood pressure greater than or equal to 160/100 mmHg, interstitial lung disease, sarcoidosis, Stage 3 or 4 cancer)
combusted or vaped cannabis use 3 days/week or more in the past 3 months
currently pregnant
not able to read an write English
Trial design
Treatments tested in this trial
- Health Assessments
Treatment groups
600 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Wisconsin, Madison
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov