The present study investigates the postprandial role of endogenous glucose-dependent insulinotropic polypeptide (GIP) on cardiovascular haemodynamics, hormone responses, and hypotensive symptoms during a tilt test.
Age 18-40 years
BMI between 18.5 and 29.9 kg/m2 (both included)
Informed consent
Allergy or intolerance to ingredients included in the mixed meal
History of Orthostatic Hypotension (OH) or Postural Orthostatic Tachycardia Syndrome (POTS) or other autonomic dysfunction at the discretion of the investigators
Anaemia (haemoglobin below normal range <7.3 mmol/L for women and <8.3 mmol/L for men)
Kidney disease (estimated glomerular filtration rate (eGFR) <90 ml/min/1.73 m2) at screening