Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality
ConditionHip Fractures
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorPeking University Shenzhen Hospital
About this trial
1. Eligible patients are randomly divided into experimental and control groups； 2. The experimental group is given esketamine combined with dexmedetomidine，while the control group is given normal saline； 3. The patients' sleep, pain, and cognition are followed up after surgery.
Eligibility criteria
Qualifiers
Age≥ 65 years old;
Hip fracture surgery under neuraxial anesthesia;
Signed informed consent.
Disqualifiers
ASA classification≥ Class V;
Presence of neuraxial anesthesia contraindications: coagulation dysfunction, thrombocytopenia, neuraxial mass, puncture site infection, etc.;
Patients with contraindications to esketamine (such as allergies, intracranial aneurysms, hyperthyroidism and glaucoma);
Patients with contraindications to dexmedetomidine (allergies);
Trial design
Treatments tested in this trial
- Esketamine combined with dexmedetomidine
- Normal saline
Treatment groups
96 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov