Effects of Exercise on Dystonia Pathophysiology

ConditionDystonia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-85
SponsorUniversity of Florida

About this trial

The purpose of this research study is to investigate how the brain and motor behavior changes in individuals with dystonia in response to exercise training.

Eligibility criteria

Qualifiers

Patients have predominantly focal cervical dystonia and whose diagnosis will be confirmed by a movement disorders specialist following criteria recommended by Movement Disorders Society.

Moderate disease severity.

Are 30 to 85 years old

Are able to tolerate exercise sessions.

Disqualifiers

Participating in an alternate structured exercise program, receiving regular physical or occupational therapy

Have significant pain, spondylosis or active arthritis

Fail the Physical Activity Readiness Questionnaire

Have significant cognitive impairment

Trial design

Treatments tested in this trial

  • Progressive resistance exercise
  • Standard of care

Treatment groups

56 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Florida

Lead sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator