About this trial
Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Group "Inactive" :No regular exercise practice (inactive people that don't follow the WHO recommendations) and have sedentary behaviors
Group "Active": Regular exercise (athletes that are specialized in aerobic exercise, with more than 300 minutes per-week over 6 months and practice at regional level).
Disqualifiers
Have sleep disorders medically diagnosed or detected by sleep forms cutoffs (clinical insomnia by ISI, severe risk of obstructive sleep apnea by Stop-Bang, bad sleep quality by PSQI.
Have a diagnosed mental health condition requiring treatment
Have renal, respiratory, cardiovascular or neuromuscular disease medically diagnosed.
Be pregnant or breastfeeding
Trial design
Crossover
Treatments tested in this trial
Aerobic Exercise
Other interventionThe exercise consists of running on a treadmill at 90% of maximum aerobic speed (MAS) for 30 minutes, followed by 12% increments every 5 minutes, until exhaustion (a "time-to-exhaustion" type of exercise).
Treatment groups
Trial outcomes
Primary outcomes
Duration of deep slow-wave sleep
Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA).
Secondary outcomes
Assessment of core temperature
Assessment of core temperature until the end of the sleep period will be measured using gastrointestinal telemetric pills (eCelsius, Bodycap®, France).
Evaluation of autonomic nervous system thermoregulation
Evaluation of autonomic nervous system thermoregulation through time-domain (R-R intervals in ms)
Evaluation of autonomic nervous system thermoregulation
Evaluation of autonomic nervous system thermoregulation through frequency- domain parameters (in Hz)
Complementary sleep evaluation
Complementary sleep evaluation through analysis of duration of N1, N2, and REM stages (in Percentage of Total Sleep Time)
Sponsors and contacts
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