Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorIstanbul Medipol University Hospital

About this trial

Spinal cord injury (SCI)-related paraplegia is a complex neurological condition characterized by motor impairment, increased spasticity, and significant functional limitations in daily activities. Spasticity is one of the most common secondary complications after upper motor neuron lesions and can negatively affect rehabilitation outcomes, gait ability, and functional independence.

This randomized controlled study aims to investigate the effects of Functional Electrical Stimulation (FES) applied to the quadriceps muscle in individuals with paraplegia. Participants will be randomly assigned to either a control group receiving conventional neurorehabilitation or an intervention group receiving additional FES treatment.

The primary outcomes include changes in spasticity level, quadriceps muscle strength, and functional mobility. Spasticity will be assessed using the Modified Ashworth Scale (MAS), muscle strength will be evaluated with Manual Muscle Testing (MMT), and functional mobility will be measured using the Spinal Cord Independence Measure (SCIM), Timed Up and Go Test (TUG), and 6-Minute Walk Test (6MWT).

The intervention period will last 8 weeks, with standardized rehabilitation programs applied to both groups. The FES group will additionally receive quadriceps stimulation with specific neuromuscular electrical stimulation parameters.

The findings of this study are expected to provide evidence regarding the effectiveness of FES as an adjunct to conventional rehabilitation in improving motor function and functional independence in individuals with paraplegia.

Eligibility criteria

Qualifiers

Aged between 18 and 65 years

Diagnosed with spinal cord injury resulting in paraplegia (traumatic or non-traumatic etiology)

Classified as ASIA Impairment Scale C or D

Medically stable condition

Disqualifiers

Presence of cardiac pacemaker or implanted electrical device

Severe cognitive impairment or communication difficulties preventing participation

Active infection or systemic inflammatory condition

Severe lower extremity contractures or deformities limiting movement

Trial design

Treatments tested in this trial

  • Conventional Neurorehabilitation
  • Functional Electrical Stimulation (FES) of Quadriceps Muscle

Treatment groups

40 Participants
are divided into 2 treatment groups

Locations

This trial has no locations