This study aims to assess the safety and efficacy of GDHT using the non-invasive Starling™ SV System in elective neurosurgery. The tested group of patients (n=70) will be compared with a control group (n=70), where hemodynamic management will be guided by standard vital signs monitoring.
Age ≥ 18 years
Elective brain surgery with an expected duration ≥ 2 h
Category 1-3 according to the ASA (American Society of Anesthesiologists) Physical Status Classification
Lateral or supine operative position
Category 4 according to the ASA Physical Status Classification
Surgery for traumatic brain injury or acute hemorrhagic stroke
Awake brain surgery
Osmotherapy before surgery (with the exception of prophylactic administration of osmotic agents according to institutional standards)
Brno University Hospital
Lead sponsor
Military University Hospital, Prague
Collaborator
Zlin Regional Hospital
Collaborator