Effects of LH and FSH on Metabolic Regulation in Cumulus Cells
ConditionUnrecognized Condition
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age35-40
SponsorKaohsiung Veterans General Hospital.
About this trial
The combined use of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has improved IVF pregnancy rates in infertile women aged 35-40, but its mechanisms remain unclear. This prospective study will examine how FSH and LH combined treatment affects cumulus cell energy metabolism. Sixty participants will be divided into two groups receiving either combined therapy or FSH alone. The study will analyze patient characteristics, infertility history, and compare mitochondrial function in cumulus cells to evaluate treatment effectiveness.
Eligibility criteria
Qualifiers
Age 35-40 years
BMI 18-30 kg/m2
planning to undergo IVF cycles
Disqualifiers
Primary ovarian insufficiency
history of oophorectomy
receiving oocyte donation
Chromosome anomaly
Trial design
Treatments tested in this trial
- FSH and LH
- FSH
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov