Effects of Multimodal Neuro Rehabilitation on Cortical Activity and Muscle Syenergy in Spastic Cerebral Palsy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-18
SponsorRiphah International University

About this trial

* To determine the effects of tDCS in conjunction with task-oriented training (TOT) and virtual reality (VR) as compared with sham stimulation and conventional physiotherapy on cortical activity and muscle synergy. * To determine the retention effects of tDCS in conjunction with task-oriented training (TOT) and virtual reality (VR) as compared with sham stimulation and conventional physiotherapy on cortical activity and muscle synergy, one-month follow-up across the five groups.

Eligibility criteria

Qualifiers

Children aged 6-18 years.

Neurologist-confirmed spastic cerebral palsy.

GMFCS Levels I-III (mild to moderate motor impairment).

Ability to understand and follow simple instructions.

Disqualifiers

Active uncontrolled epilepsy or history of seizure in the last year.

Metal implants in the head or implanted medical/electrical devices (e.g., cochlear implants, ventriculoperitoneal shunts, pacemakers).

Significant visual or auditory impairments that would interfere with task performance.

Severe behavioral or cognitive difficulties that would prevent safe application of tDCS or training tasks.

Trial design

Treatments tested in this trial

  • Active Anodal Transcranial Direct Current Stimulation (tDCS) + Task-Oriented Training
  • Sham Active Anodal Transcranial Direct Current Stimulation + Task-Oriented Training
  • Active Anodal Transcranial Direct Current Stimulation + Virtual Reality
  • Sham Active Anodal Transcranial Direct Current Stimulation + Virtual Reality
  • Conventional Physiotherapy

Treatment groups

150 Participants
are divided into 5 treatment groups

Locations

This trial has no locations