About this trial
* To determine the effects of tDCS in conjunction with task-oriented training (TOT) and virtual reality (VR) as compared with sham stimulation and conventional physiotherapy on cortical activity and muscle synergy. * To determine the retention effects of tDCS in conjunction with task-oriented training (TOT) and virtual reality (VR) as compared with sham stimulation and conventional physiotherapy on cortical activity and muscle synergy, one-month follow-up across the five groups.
Eligibility criteria
Qualifiers
Children aged 6-18 years.
Neurologist-confirmed spastic cerebral palsy.
GMFCS Levels I-III (mild to moderate motor impairment).
Ability to understand and follow simple instructions.
Disqualifiers
Active uncontrolled epilepsy or history of seizure in the last year.
Metal implants in the head or implanted medical/electrical devices (e.g., cochlear implants, ventriculoperitoneal shunts, pacemakers).
Significant visual or auditory impairments that would interfere with task performance.
Severe behavioral or cognitive difficulties that would prevent safe application of tDCS or training tasks.
Trial design
Treatments tested in this trial
- Active Anodal Transcranial Direct Current Stimulation (tDCS) + Task-Oriented Training
- Sham Active Anodal Transcranial Direct Current Stimulation + Task-Oriented Training
- Active Anodal Transcranial Direct Current Stimulation + Virtual Reality
- Sham Active Anodal Transcranial Direct Current Stimulation + Virtual Reality
- Conventional Physiotherapy