The objectives is to evaluate the effect of omega-3 fatty acids in old participants with polyvascular disease on immune parameters and inflammatory mediators at different times. Three modalities of administration of omega-3 will be compared with a placebo (olive oil): predominant EPA (Eicosapentaenoic acid), predominant DHA (doxosahexaenoic acid), and combinaison of both. This study will measure the level of omega3 fatty acids in this population 4 hours after taking, on the 7th day, on the 21th day of administration and 1 month after administration.
≥ 75 years old
Patients with polyvascular disease in cases of vascular lesions in ≥2 disease territories or any combination of coronary, peripheral, or carotid artery disease.
Able to comply with the requirements of the study protocol
Signed informed consent form approved by the ethical committee
Inflammatory syndrome (CRP >10 mg/l) on day 0 and day 7
Acute illness or event during the time of intervention
Université Libre de Bruxelles
Lead sponsor
University of Mons
Collaborator
Université Catholique de Louvain
Collaborator