About this trial
The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).
Eligibility criteria
Qualifiers
Histologically proven cancer in association with a pregnancy (during pregnancy or cancer dagnosis within 5 years after pregnancy)
> 18 years of age, premenopausal
Patients who have given their signed and written informed consent to participate in the trial after fully understanding the implication of the protocol
Women receiving any cytotoxic drug or radiation therapy during pregnancy are allowed for the assessment of the maternal and fetal outcome (Part II).
Disqualifiers
Mentally disabled or significantly altered mental status that would prohibit the understanding and giving of informed consent
Mentally disabled or significantly altered mental status that would prohibit the understanding and giving of informed consent
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
University Hospital, Gasthuisberg
Lead sponsor
The Netherlands Cancer Institute
Collaborator
Erasmus Medical Center
Collaborator
San Gerardo Hospital
Collaborator
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Collaborator
Charles University, Czech Republic
Collaborator