This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction. Additionally, it evaluates how cardiorespiratory fitness, cardiovascular health, psychosocial factors, sleep quality, stress, and cognitive function relate to reproductive outcomes.
Voluntary written informed consent of the participant has been obtained prior to any screening procedures
Age 18-43
Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET)
Any reduction in general state of health preventing from performing hormonal stimulation for MAR
Absolute and relative contraindications for cardiopulmonary exercise testing (CPET) - No pregnancy at initial screening - Current illicit drug abuse including daily marijuana and CBD consumption (alcohol ≤2 drinks per day allowed)
Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease)
Severe renal impairment (e.g. estimated glomerular filtration rate <30 ml/min/m2)