About this trial
A Single-Center, Prospective Observational Cohort Study Comparing Perioperative Electroencephalographic Anesthesia Depth Parameters (Electroencephalographic Index, SE/RE Entropy, Burst Suppression Ratio) Between Patients With Preoperative Sleep Disorders and Those Without; To Identify the Independent Effects of Preoperative Sleep Disorders on the Speed of Electroencephalographic Recovery During Emergence, Electroencephalographic Status at Extubation, Intra-PACU Electroencephalographic Fluctuations, and Quality of Emergence.
Eligibility criteria
Qualifiers
- Aged 18 to 65 years, with American Society of Anesthesiologists (ASA) physical status classification Ⅰ-Ⅲ;
Elective non-cardiac surgery with an expected operative duration longer than 2 hours;
Preoperative Mini-Mental State Examination (MMSE) score ≥ 24;
Completion of the Pittsburgh Sleep Quality Index (PSQI) assessment 1 day before surgery;
Disqualifiers
Preoperative severe cognitive dysfunction, history of traumatic brain injury or stroke;
Long-term regular use of sedative-hypnotics, antidepressants or antipsychotics;
Intraoperative massive hemorrhage, cardiac arrest, or severe hypoxemia (SpO₂ < 90% lasting for more than 5 minutes);
Inability to cooperate with EEG monitoring or scale evaluation;
Trial design
Treatments tested in this trial
- Exposed cohort (sleep disorder group)
- Control cohort (non-sleep disorder group)