Effects of Preoperative Sleep Disorders on Perioperative Anesthesia Depth and Recovery Quality in Patients Undergoing Noncardiac Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorGeneral Hospital of Ningxia Medical University

About this trial

A Single-Center, Prospective Observational Cohort Study Comparing Perioperative Electroencephalographic Anesthesia Depth Parameters (Electroencephalographic Index, SE/RE Entropy, Burst Suppression Ratio) Between Patients With Preoperative Sleep Disorders and Those Without; To Identify the Independent Effects of Preoperative Sleep Disorders on the Speed of Electroencephalographic Recovery During Emergence, Electroencephalographic Status at Extubation, Intra-PACU Electroencephalographic Fluctuations, and Quality of Emergence.

Eligibility criteria

Qualifiers

- Aged 18 to 65 years, with American Society of Anesthesiologists (ASA) physical status classification Ⅰ-Ⅲ;

Elective non-cardiac surgery with an expected operative duration longer than 2 hours;

Preoperative Mini-Mental State Examination (MMSE) score ≥ 24;

Completion of the Pittsburgh Sleep Quality Index (PSQI) assessment 1 day before surgery;

Disqualifiers

Preoperative severe cognitive dysfunction, history of traumatic brain injury or stroke;

Long-term regular use of sedative-hypnotics, antidepressants or antipsychotics;

Intraoperative massive hemorrhage, cardiac arrest, or severe hypoxemia (SpO₂ < 90% lasting for more than 5 minutes);

Inability to cooperate with EEG monitoring or scale evaluation;

Trial design

Treatments tested in this trial

  • Exposed cohort (sleep disorder group)
  • Control cohort (non-sleep disorder group)

Treatment groups

80 Participants
are divided into 2 treatment groups