About this trial
To explore the effects and possible mechanisms of dexmedetomidine combined with taVNS on the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic surgery
Eligibility criteria
Qualifiers
Women aged 18 to 65;
Elective laparoscopic surgery under general anesthesia;
Classified as American Society of Anesthesiologists (ASA) physical status I to II;
Capable of understanding the study procedures and various assessment scales and able to effectively communicate with the researchers;
Disqualifiers
Patients with ASA anesthesia classification ≥ III;
Poorly controlled hypertension, atrioventricular block ≥ second degree, obesity (BMI > 30 kg/m²);
Pregnant or breastfeeding;
Known allergy to drugs used in the study protocol, history of traumatic brain injury, history of gastrointestinal surgery;
Trial design
Treatments tested in this trial
- Transcutaneous Auricular Vagus Nerve Stimulator
- Dexmedetomidine