Effects of taVNS Combined With Dexmedetomidine on POVN

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-65
SponsorAffiliated Hospital of Nantong University

About this trial

To explore the effects and possible mechanisms of dexmedetomidine combined with taVNS on the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic surgery

Eligibility criteria

Qualifiers

Women aged 18 to 65;

Elective laparoscopic surgery under general anesthesia;

Classified as American Society of Anesthesiologists (ASA) physical status I to II;

Capable of understanding the study procedures and various assessment scales and able to effectively communicate with the researchers;

Disqualifiers

Patients with ASA anesthesia classification ≥ III;

Poorly controlled hypertension, atrioventricular block ≥ second degree, obesity (BMI > 30 kg/m²);

Pregnant or breastfeeding;

Known allergy to drugs used in the study protocol, history of traumatic brain injury, history of gastrointestinal surgery;

Trial design

Treatments tested in this trial

  • Transcutaneous Auricular Vagus Nerve Stimulator
  • Dexmedetomidine

Treatment groups

176 Participants
are divided into 2 treatment groups