Effects of Transcutaneous Electrical Phrenic Nerve Stimulation and Transcutaneous Electrical Diaphragmatic Stimulation

ConditionDiaphragm
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorHospital Sirio-Libanes

About this trial

Transcutaneous electrical phrenic nerve stimulation (TEPNS) and transcutaneous electrical diaphragm stimulation (TEDS) are modalities that use surface electrodes placed on the patients' skin to generate action potentials and contractions of the muscle fibers of the diaphragm. The primary objective will be to evaluate the efficacy of TEPNS and TEDS in healthy adult individuals. Secondary objectives will be to assess the feasibility, safety, and level of discomfort reported by the individual resulting from the application of TEPNS and TEDS.

Eligibility criteria

Qualifiers

Age between 18 and 60 years;

Normal pulmonary function test, without alterations, assessed through spirometry;

Body Mass Index (BMI) between 18.5 and 24.9 kg/m2.

Disqualifiers

Smokers or former smokers;

Individuals with previously known cardiopulmonary diseases (restrictive lung diseases, chronic obstructive pulmonary disease - COPD, asthma, cystic fibrosis, among other pathologies);

Presence of implanted electrical devices (pacemaker, implantable cardioverter-defibrillator, among others);

Individuals who have contraindications to undergo evaluation and/or application of transcutaneous electrical stimulation of the diaphragm muscle, such as: altered sensitivity, wounds at the site of application, deformities, among other conditions.

Trial design

Treatments tested in this trial

  • Transcutaneous electrical phrenic nerve stimulation (TEPNS)
  • Transcutaneous electrical diaphragm stimulation (TEDS)

Treatment groups

12 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Hospital Sirio-Libanes

Lead sponsor

Hospital Israelita Albert Einstein

Collaborator