About this trial
The aim of this study is to explore the efficacy and safety of poly -LRB-cinnamyl alcohol) foam in the treatment of venous malformations of head and neck through a prospective randomized clinical trial, this trial may provide better treatment options and evidence for head and neck VMs.
Eligibility criteria
Qualifiers
Age 14-60 years of age, sex unlimited (except pregnant women or those preparing for pregnancy)
Clinical diagnosis and imaging () were consistent with head and neck venous malformations
Participants volunteered to participate in the trial and signed an informed consent form.
Disqualifiers
People with serious systemic diseases, including heart disease, high blood pressure, diabetes, etc. , that are not under control. Heart Attack: 1. Recent frequent attacks of angina. 2. Recent history of myocardial infarction 3. Cardiac function grade iii-iv or with symptoms of sitting breathing, cyanosis, jugular venous distension, lower limb edema, etc. . 4. Heart disease complicated with hypertension 5. Type II or III Type II atrioventricular block, double bundle branch block, as syndrome, diabetes: blood sugar control in 8.88 mmol/L above, hypertension: after taking medicine blood pressure can not be controlled in the normal range namely systolic pressure below 140 mmhg, diastolic pressure below 90 mmhg)
Patients who are unable to follow up on time;
Persons who are mentally ill or have mental disorders;
The patient or his/her authorized person is unwilling to sign a written informed consent or comply with the protocol
Trial design
Treatments tested in this trial
- The addition of sodium hyaluronate to poly (cinnamyl alcohol-RRB- produces a more stable foam