Efficacy and Safety of Auto-FMT in Preventing aGVHD

ConditionGraft Versus Host Disease, Acute

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-60

SponsorThe First Affiliated Hospital of Soochow University

About this trial

To evaluation the efficacy and safety of autologous fecal bacteria transplantation in preventing acute graft versus host disease after haploidentical hematopoietic stem cell transplantation. Bone marrow transplant patients were recruited.

Eligibility criteria

Qualifiers

Haplo-HSCT patients; Bacteroidetes >0.1%; inverse Simpson diversity ≥2

Disqualifiers

Gastrointestinal diseases；Age>60; or Age<10；Probiotics or prebiotics were taken before enrollment

Trial design

Treatments tested in this trial

autologous fecal bacteria

Treatment groups

100 Participants

are divided into 2 treatment groups

Sponsors and collaborators

The First Affiliated Hospital of Soochow University

Lead sponsor

Source ClinicalTrials.gov