A multicenter, randomized, open-label, blinded-endpoint trial with a concurrent prospective observational cohort to compare bailout intracranial angioplasty or stenting versus standard therapy on functional outcome, stroke recurrence, and mortality in patients with acute intracranial atherosclerotic stenosis-related large vessel occlusion after thrombectomy.
Age≥18 years.
Time interval from symptom onset to puncture ≤24 hours.
National Institute of Health Stroke Scale (NIHSS) Score ≥6 before randomisation.
Pre-stroke modified Rankin Scale (mRS) of 0-2.
Any sign of intracranial hemorrhage (ICH, except microbleeds) on baseline brain imaging.
CT or MR imaging evidence of intracranial tumor (except small meningiomas or cerebral aneurysms < 3mm in diameter).
Any indication of intracranial vessel perforation during thrombectomy..
Presence of tandem lesion in the extracranial segment of the internal carotid artery or vertebral artery, or intracranial arterial stenosis with distal vessel occlusion..
Feng Gao
Lead sponsor
Beijing Tiantan Hospital
Sponsor institution