About this trial
The aim of this clinical trial is to investigate whether pulsatile compression therapy can support heart and kidney function in patients admitted with acute heart failure and fluid accumulation in the legs.
Pulsatile compression boots, which provide pulsatile compression therapy, work by adding a predefined pressure to the legs in a rhythm that enhances mobilization of peripheral edema and improves venous and lymphatic drainage from the lower extremities. This increased venous return (preload) may allow the heart to fill more effectively and pump more strongly, thereby improving circulation. Better circulation can enhance kidney blood flow, help diuretics work more efficiently, and reduce the risk of complications due to worsening heart failure, affecting both the heart and kidneys.
The investigators want to explore whether adding this therapy to standard diuretic treatment is safe, feasible, and offers benefits compared with standard diuretic treatment alone.
Participants will receive three daily sessions of pulsatile compression therapy alongside usual clinical care.
Eligibility criteria
Qualifiers
Capable of giving written informed consent
Inclusion within 24 hours from admission
Bilateral LE edema - defined as: Pitting edema scale > 1, bilaterally
Initial IV diuretic treatment
Disqualifiers
Pregnancy
Life expectancy less than 1 year for any reason
Expected hospital stay less than 1 day
New York Heart Association classification (NYHA) class IV
Trial design
Treatments tested in this trial
- Pulsatile Compression Boots (PCB)