Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBeijing Tiantan Hospital

About this trial

The aim of this study is to assess the efficacy and safety of endovascular treatment versus medical management in patients with acute basilar artery occlusion with extended time window of 24-72 hours from onset.

Eligibility criteria

Qualifiers

Age≥18 years

Acute basilar artery occlusion confirmed by CTA, MRA, or DSA

Pre-stroke mRS of 0-2

NIHSS score ≥ 10 before randomization

Disqualifiers

Any sign of intracranial hemorrhage (except microbleeds) on brain imaging prior to randomization

Complete cerebellar infarct with significant mass effect, or bilateral thalamic infarction as evidenced by baseline neuroimaging

CT or MRI evidence of intracranial tumor (except small meningioma and cerebral aneurysm < 3mm in diameter)

Known or highly suspected chronic occlusion of basilar artery

Trial design

Treatments tested in this trial

  • Best medical management
  • Endovascular treatment

Treatment groups

224 Participants
are divided into 2 treatment groups

Sponsors and collaborators