About this trial
Despite pharmaceutical innovations, chemotherapy induced nausea is frequent and largely participating to alter our patients quality of life.
Non invasive vagal stimulation is approved in other health issues, for example in headache or gastroparesis, with a reported benefit on nausea.
This study aims to analyse if a non invasive vagal stimulation could better prevent chemotherapy induced nausea, in addition to standard treatment, in breast cancer patients treated with cyclophosphamide and anthracycline.
Eligibility criteria
Qualifiers
Eastern Cooperative Oncology Group (ECOG) status 0 to 2
patient with breast cancer planned to receive Anthracycline and Cyclophosphamide chemotherapy
informed consent
compliance expected
Disqualifiers
nausea or vomiting 24h or less, before inclusion
Antiemetic drug intake in the last 72h before inclusion
Central nervous system metastasis
Daily alcohol intake
Trial design
Treatments tested in this trial
- non invasive auricular vagal stimulation
- usual medical treatment
- sham stimulation