Efficacy and Safety of Retrograde Intraarticular Injection, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Femoral Neck Fractured Patients Undergoing Cementless Bipolar Hemiarthroplasty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorKing Chulalongkorn Memorial Hospital

About this trial

The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are:

* The efficacy in reducing blood transfusion for topical tranexamic acid administration * The safety of tranexemic acid, topically used

As having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration.

Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion.

Eligibility criteria

Qualifiers

Elderly patients (age > 60 years)

Femoral neck fractures from low energy mechanism

Household ambulator

Undergoing cementless bipolar hemiarthroplasty at KCMH

Disqualifiers

Allergy to TXA

History of VTE

History of hip surgery, pathological fracture, hip infection

Congenital or acquired coagulopathy

Trial design

Treatments tested in this trial

  • Topical tranexamic acid administration

Treatment groups

75 Participants
are divided into 3 treatment groups