About this trial
This study is a multicenter, prospective, observational study aimed at investigating the efficacy and safety of triple targeted drug therapy in patients with arterial pulmonary hypertension (PAH) who are not at low risk and are receiving initial treatment. The prognosis of arterial pulmonary hypertension is explored.
Eligibility criteria
Qualifiers
Consent and sign the informed consent form
Non-low-risk PAH treatment-naive patients
Disqualifiers
Positive acute vascular response test for idiopathic/hereditary/drug-related arterial pulmonary hypertension
Pulmonary veno-occlusive disease/pulmonary capillary hemangiomatosis (PVOD/PCH) with arterial pulmonary
Pregnant or lactating women
Suffering from mental illness or cognitive impairment
Trial design
Treatments tested in this trial
- Endothelin receptor antagonist (ERA) combined with PDE5i/sGC agonist dual therapy prostacyclin drugs
Treatment groups
Sponsors and collaborators
Qianfoshan Hospital
Lead sponsor
Chinese Academy of Medical Sciences, Fuwai Hospital
Collaborator
Jianghan University Affiliated Hospital
Collaborator