Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorNantes University Hospital
About this trial
The objective of this study is to demonstrate that an \< or equal to 8-hour time-restricted eating (i.e., fasting for at least 16 hours every day), not focusing on reducing caloric intake, reduces intra-hepatic fat in patients with obesity and Metabolic dysfunction-Associated Steatotic liver Disease (MASLD).
Eligibility criteria
Qualifiers
Body mass index (BMI) between 30.0 and 49.9 kg/m2
Age between 18 and 65 years (limits included)
Sedentary (light-intensity physical activity less than 1 hour per week) or moderately active (moderate exercise 1 to 2 hours per week). Self-declared criteria.
Weight stable for at least 3 months prior to the beginning of the study (gain or loss <4 kg). Self-declared criteria.
Disqualifiers
Alcohol intake > 20 g/day
Night-shift workers or rotating shift workers
Smoking
Patient with diabetes if HbA1c not at target (<7%) and/or using a non-authorized medication)
Trial design
Treatments tested in this trial
- Time Restricted Eating
- Usual care only
Treatment groups
72 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov