Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease
ConditionDupuytren's Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorElsan
About this trial
Dupuytren's disease is a frequent hereditary disease in Northern Europe. It is a degenerative disease affecting the palmar aponeurosis of the hand. It develops a progressive contractile fibrosis which cuts the hypodermic fatty tissue, adheres to the skin and the phalanges, gradually bending the affected rays, resulting in significant functional impotence.
Various medical and surgical treatments are available.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Carrier of Tubiana stage II-IV Dupuytren's disease on at least one or more rays, not previously operated
Indication of a surgery by aponeurectomy
Skin pinch of the posterior aspect of the arm of more than 1cm
Disqualifiers
Previous surgery of any kind for Dupuytren's disease
Involvement on the thumb only
Need for a total skin graft or a pedicle flap on all the rays to be treated
Active autoimmune disease
Trial design
Treatments tested in this trial
- Aponeurectomy with grafting
- Aponeurectomy alone
Treatment groups
172 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov