This randomized, interventional study evaluates the efficacy of Collagendep Pink Beauty, an oral nutritional supplement, in reducing vulvar dryness in women with Genital Lichen Sclerosus (VLS) who are undergoing fat grafting treatment. Lichen sclerosus is a chronic inflammatory condition that leads to tissue hardening, loss of elasticity, and significant symptoms such as itching, pain, and dryness, which severely impact functional and emotional well-being. While fat grafting is a recognized regenerative therapy for stabilizing the disease, this study investigates whether a 4-month course of bioactive collagen peptides and functional ingredients can further improve mucosal hydration and symptom relief compared to fat grafting alone.
Female patients aged 18 years or older.
Clinical diagnosis of Genital Lichen Sclerosus.
Patients with a clinical indication for autologous fat grafting (lipofilling) treatment.
Ability to provide written informed consent.
Presence of active local or systemic infections.
Current pregnancy or breastfeeding.
Known hypersensitivity or allergy to any of the ingredients of the study product "Collagendep Pink Beauty" (e.g., collagen, hyaluronic acid, herbal extracts).
Concurrent use of other oral supplements that might interfere with the evaluation of the study results.