Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study)
ConditionSevere Dengue
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-99
SponsorChulalongkorn University
About this trial
The goal of this randomized double-blinded placebo-controlled trial is to learn about dexamethasone and the treatment of severe dengue population. The main question it aims to answer are steroid therapy may be effective in dengue.
Eligibility criteria
Qualifiers
Laboratory confirmed Dengue infected patients (Positive NS1 Ag or anti-DENV IgM by Dengue Duo test)
And still in febrile phase (Body temp>37.5 C)
Shock : Sys<90mmHg or Narrow PP (<20mmHg) orTachycardia (pulse>100/min) with Hematocrit decreased ≥20 %
Fluid accumulation and respiratory distress
Disqualifiers
Severe dengue> 24 hrs
Dengue without warning signs
Pregnancy
Patient who receieved any steroid within 1 week
Trial design
Treatments tested in this trial
- Dexamethasone
- Placebo
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov