Efficacy of Hi-tACS for Schizophrenia Negative Symptoms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Mental Health Center
About this trial
The goal of this clinical trial is to investigate whether Hi-tACS is effective and safe in treating negative symptoms of schizophrenia.
Schizophrenic patients will receive treatment (Hi-tACS or shame stimulation) for 2 weeks.
Negative symptoms, cognitive functioning, social functioning, and quality of life of intervention group and control group were assessed and compared between the two groups at baseline, 2 weeks, and 3 months post-intervention.
Eligibility criteria
Qualifiers
Han Chinese population;
Age ≥ 18 years;
Education level ≥ 6 years, able to fill out questionnaires on their own, and having sufficient audiovisual level to complete the necessary examinations;
Meets DSM-5 diagnostic criteria for schizophrenia as assessed by MINI 7.0;
Disqualifiers
Meets DSM-5 diagnostic criteria for other mental disorders;
Total score ≥19 on the PANSS positive subscales (P1-P7) ;
Severe negative symptoms that prevent the patient from completing the required assessments and interventions;
Serious physical or central nervous system disease (intracranial infection, intracranial tumor, presence of metal objects in the skull; epilepsy, seizures; history of hydrocephalus or central nervous system tumors; with implanted electronic devices; serious cardiac disease and fitted with a pacemaker, etc.);
Trial design
Treatments tested in this trial
- High-intensity transcranial alternating current stimulation (Hi-tACS)
- Sham High-intensity transcranial alternating current stimulation (Sham-Hi-tACS)
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov