Efficacy of Individualized Aerobic Exercise Training in Patients With Inflammatory Bowel Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorNingbo Medical Center Lihuili Hospital

About this trial

The goal of this clinical trial is to learn if a 12-week individualized aerobic training program helps manage inactive or mildly active inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) in adult patients aged 18-65 years. It will also assess participant compliance and the safety of the training program. The main questions it aims to answer are:

1. Does this aerobic training program improve the cardiopulmonary function of participants? 2. Does this aerobic training program help control disease activity? 3. Does this aerobic training program improve participants' quality of life?

Researchers will divide participants into two groups. One group will participate in the training program directly. The other group will first undergo a 12-week control intervention (i.e., standard treatment) before proceeding to the training program.

Participants will:

1. Take part in the individualized aerobic training program according to their baseline physical activity level for 12 weeks. 2. Visit the clinic once every 4 weeks for check-ups and tests. 3. Keep a diary of symptoms.

Eligibility criteria

Qualifiers

Diagnosed with CD or UC for more than 3 months.

Disease activity in remission or mildly active (CD: CDAI < 220; UC: pMS < 5).

Baseline physical activity intensity is low, measured by the IPAQ Chinese version short form, and without a habit of "regular exercise".

Agree to participate in the study and accept a 12-week individualized aerobic exercise training program.

Disqualifiers

Pregnant or breastfeeding, or planning to become pregnant within the next 3 months.

Presence of physical movement disorders or other chronic diseases that limit physical activity.

Having an ileostomy.

History of anal or intestinal surgery within the past 3 months.

Trial design

Treatments tested in this trial

  • 12-week individualized aerobic exercise training
  • 12-week control intervention followed by 12-week aerobic exercise training

Treatment groups

28 Participants
are divided into 2 treatment groups