Efficacy of Mindfulness in PREventing Progression to Psychosis in Individuals With an Ultra High Risk for Psychosis

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorCentre Psychothérapique de Nancy

About this trial

The main objective is to evaluate the efficacy of a group-based mindfulness therapy programme in reducing distress associated with symptoms of UHR (Ultra High Risk) or FEP (first psychotic episode) compared with usual treatment. The secondary objectives were to study the efficacy of a group-based mindfulness intervention: on the reduction of psychotic symptoms; on the maintenance over time (6 months of follow-up) of the efficacy of the intervention on the distress associated with the symptoms of the UHR or PEP state; and on various dimensions associated with care: cognitive functions, anxiety, quality of life.

Eligibility criteria

Qualifiers

People aged between 18 and 30 validating the criteria for UHR or PEP status on the CAARMS scale and having a social functional impact (SOFAS score below 50 or a reduction of more than 30% in the score)

Disqualifiers

Previous episode of schizophrenic disorder, schizoaffective disorder or bipolar disorder

Previous antipsychotic treatment for more than 12 months

Organic mental disorder or intellectual disability

Serious suicidal/homicidal risk (but admissible if this risk has been resolved)

Trial design

Treatments tested in this trial

  • MBTP : Mindflulness based training for psychosis

Treatment groups

270 Participants
are divided into 2 treatment groups