Efficacy of Neoadjuvant Immunotherapy in Patients With Lung Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-79
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

The goal of this observational study is to learn about the long-term effects of neoadjuvant immunotherapy in patients with lung cancer. The main questions it aims to answer are:

* Does pneumonectomy bring more benefits for pateints than lobectomy? * Does surgery bring more benefits for patients than non-surgery modalities (such as radiotherapy) after neoadjuvnat immunotherapy? Participants will receive neoadjuvant treatment and the study will analyze the data.

Eligibility criteria

Qualifiers

Aged between 18 and 79 years;

Received at least two cycles of neoadjuvant immunotherapy;

ECOG performance status score of 0;

Complete clinical information including imaging data available.

Disqualifiers

Diagnosed with or suspected active autoimmune diseases;

Presence of EGFR/ALK sensitive mutations;

Pregnant or breastfeeding women;

Previous anti-tumor therapies including chemotherapy or radiotherapy;

Trial design

Treatments tested in this trial

  • Pneumonectomy
  • lobectomy
  • radiotherapy
  • Anti-Tumor Drugs

Treatment groups

500 Participants
are divided into 2 treatment groups