Bleeding is the most frequently reported serious complication of endoscopic sphincterotomy, and severe bleeding has occurred in about 1% to 2% of patients. Endoscopic injection of epinephrine is the most commonly used, effective, and least expensive method for the management of post- sphincterotomy bleeding. However, the efficacy of prophylactic saline-epinephrine solution injection to prevent delayed EST bleeding when transient bleeding During ERCP has not been established.
Age 20 years or older.
Ability to give informed consent.
An naive major papilla.
Transient bleeding after endoscopic sphincterotomy
Prior endoscopic sphincterotomy.
Thrombocytopenia (platelets <50,000/mm3).
Liver cirrhosis (Child A-C)
CKD stage 4-5 and dialysis.
Wen-Hsin Huang
Lead sponsor
China Medical University Hospital
Sponsor institution