Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
ConditionOsteoarthritis Hand
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form. There is currently no etiological treatment for osteoarthritis. Symptomatic treatments have a modest efficacy, which justifies the search for new treatments. The surgical options are arthrodesis or prosthesis, invasive techniques potentially sources of complications, and finally proposed infrequently given the prevalence of digital osteoarthritis.
DECAD is a prospective phase II trial aimed at evaluating the efficacy of surgical joint denervation in painful digital osteoarthritis.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Patients with symptomatic digital osteoarthritis according to the criteria of the American College of Rheumatology
1 painful PIP joint (Analog digital scale ≥ 4/10) for more than 3 months
having failed the usual medical treatment for a minimum of 3 months (level 1 analgesics, NSAIDs, infiltrations)
Disqualifiers
digital osteoarthritis secondary to other known causes (eg gout, reactive arthritis, RA, psoriatic arthritis, spondyloarthropathies, septic arthritis)
anesthetic contraindications to surgery or to performing an MRI
Existence of a pain syndrome in the upper limbs, which would interfere with the assessment of AD.
Fibromyalgia
Trial design
Treatments tested in this trial
- Surgical Denervation
Treatment groups
19 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov