Efficacy of the RayerKnife X Stereotactic Radiotherapy System in the Treatment of Brain Metastases

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorTianjin Medical University Cancer Institute and Hospital

About this trial

The goal of this clinical trial is to evaluate the efficacy of stereotactic radiotherapy in the treatment of brain metastases. The main question it aims to answer is: Did stereotactic radiotherapy improve LC rate in the treatment of brain metastases? Participants will be recorded for local control rates during follow-up.

Eligibility criteria

Qualifiers

Age between 18 and 80 years (inclusive), regardless of gender.

Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2.

Diagnosis of brain metastasis confirmed by histopathological examination and/or imaging, and deemed suitable for stereotactic radiotherapy according to the investigator's judgment.

Tumor diameter of brain metastasis ≤ 4 cm, with ≤ 10 metastatic lesions.

Disqualifiers

Expected survival time < 6 months.

Patients requiring surgical treatment or other local therapies for the target lesions during radiotherapy.

Patients who have received other local treatments (including radiofrequency ablation, cryoablation, particle therapy, etc.) within 30 days prior to screening, or those who have received systemic therapy (chemotherapy, endocrine therapy, immunotherapy) within 14 days or less than five half-lives of a drug prior to screening (whichever is longer).

Patients who have previously received radiotherapy at the same site or for the same lesion.

Trial design

Treatments tested in this trial

  • X-ray stereotactic radiotherapy for brain metastasis

Treatment groups

34 Participants
are divided into 1 treatment group

Locations

This trial has no locations