Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
ConditionGonarthrosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-75
SponsorBengu Turemenogullari
About this trial
The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic. Current conservative treatments have moderate effects on chronic knee pain and their use is limited due to the risk of side effects. In addition to pain, patients also experience other symptoms.
As a result of the osteoarthritis process, prorioception in the knee is impaired with a decrease in mechanoreceptors, resulting in loss of balance and an increase in the risk of falling.
Eligibility criteria
Qualifiers
Age between 30-75
Chronic knee pain that lasts at least 6 months
Radiographic confirmation of osteoarthritis: Presence of Grade 3 or 4 radiographic changes characterized by significant narrowing in the medial space of the tibiofemoral joint according to the Kellgren-Lawrence classification system
Knee pain >40 mm when performing one of the two movements that cause the most severe pain (sitting to standing or going up and down stairs) according to 100 mm VAS
Disqualifiers
Presence of systemic inflammatory disease such as rheumatoid arthritis
Previous RFA treatment to the knee or hyaluronic acid or steroid injection to the knee within the last 3 months
History of previous knee surgery
Clinically significant structural abnormalities other than osteoarthritis that may lead to chronic knee pain
Trial design
Treatments tested in this trial
- 2-point Radiofrequency Ablation
- 3-point Radiofrequency Ablation
- 5-point Radiofrequency Ablation
Treatment groups
66 Participants
are divided into 3 treatment groupsSponsors and collaborators
Bengu Turemenogullari
Lead sponsor
Ankara Etlik City Hospital
Sponsor institution
Source ClinicalTrials.gov