Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCharles University, Czech Republic
About this trial
FILTRex is a single-centre, controlled, randomised, prospective, non-inferiority clinical trial to compare the efficiency and safety of prolonged (72-hours) versus standard (24-hours) duration of use for Heat and Moisture Exchange (HME) filters in adult mechanically ventilated critically ill patients
Eligibility criteria
Qualifiers
Age ≥18 years
In-patient in ICU and expected to stay > 3 days
Mechanical ventilation or imminent need of it; predicted length of mechanical ventilation ≥ 72h
Clinical Pulmonary Infection score (CPIS) less than six at the baseline 5 No history and symptoms of aspiration at the baseline
Disqualifiers
Suspected pulmonary infection on admission and in the first 48 hours of mechanical ventilation
Pregnancy
Acute respiratory distress syndrome
Body temperature < 32°C
Trial design
Treatments tested in this trial
- 72-hour HME exchange interval group
- 24-hour HME exchange interval group
Treatment groups
120 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov