This exploratory study aims to investigate the effect of Electrical Impedance Tomography (EIT)-guided ventilator settings on mechanical power in patients with acute hypoxemic respiratory failure (AHRF), including both ARDS and non-ARDS conditions. Mechanical power, a key factor associated with ventilator-induced lung injury (VILI), will be measured before and after EIT-guided PEEP titration. The study will evaluate feasibility and changes in lung mechanics, gas exchange, and EIT parameters. A total of 17 patients requiring invasive mechanical ventilation will be enrolled at Siriraj Hospital, Mahidol University.
Age ≥ 18 years
Diagnosed with acute hypoxemic respiratory failure within 48 hours
Expected to require invasive mechanical ventilation ≥ 48 hours
On mechanical ventilation within 24 hours
Pregnancy
Body mass index (BMI) > 40 kg/m2
Contraindications to using electrical impedance tomography, including
Presence of a pacemaker or automatic implantable cardioverter-defibrillator (AICD)